If you need to have it done by a yard, I think the cost would make the job prohibitive, especially given the current market value of a 43 DC with the queen already in. I also think that although it's not a job for the faint at heart, someone with a fair amount of skill, time and equipment can accomplish the job. Mad Hatta, I don't know where you are located, but if you are anywhere near So Fla, you may want to try to get in touch with Pascal on this site. He is in the process of doing a major interior refit on his 53 and although it is a much larger boat, he may still be able to give you lots of good advice.
Now, after saying the above, I think the job could be done fairly easy. While the fuel tanks are located under the twin berths (200 gals each) they can be removed by carefully cutting into the tabbing that holds them down. Re plumbing won't be difficult for the fuel lines. Take out the center line dresser and plan carefully to allow space between the steering gear and the front of the fuel tanks. You will need to build a proper support system to remount them and glass them in.
After planning that you should have plenty of space around the queen bed on the port/starboard and foot end of the bed. Now you can plan stuff like end tables and port and starboard dressers with drawers. If you really want to simplify the planning stage, just find a 43 DC with a factory queen and plan from it. Keep in mind that the encasement for the present twin fuel tanks will be wider than the factory queen installation. The fuel capacity of the factory queen set up under the bed is less than 300 gals, compared to twin 200 gal tanks. You may have to have the p/s dressers made less deep to give you adequate space on each side of the bed. Not so terrible and you can perhaps get a much bigger master bed in there.
Years ago I owned two 43DC's. An early (73) with twins and a later model with the queen. I think the queen set up is much better.
Good luck with your project....one requirement of this forum is when you ask for information regarding a project such as yours is that if you go for it, you will need to post lots of pictures as you progress. LOL.
Walt